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Pathophysiology, Diagnosis, and Management with Online Resource

ISBN: 9780521514262

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Pathophysiology, Diagnosis, and Management with Online Resource

Διαθεσιμότητα: 23-28 ημέρες


  • In light of recent advances in scientific understanding, this textbook provides a comprehensive yet focused guide to anemia, the most common hematologic malady in medicine. This authoritative, clinical resource covers the scientific basis of the many forms of anemia, while offering a practical approach to prognosis, diagnosis and management. Chapters cover a multitude of topics, ranging from the basic components and physiologic functions, to secondary anemias and transfusion therapy. Modern in approach, this text also looks ahead to new and innovative methodologies. With recommended treatment plans and many case studies, this heavily-illustrated book is essential reading for hematologists and oncologists. In providing a pathophysiologic context, it is also of interest to nurse practitioners, physician assistants and medical students in the field. This book provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.​


    • Provides pathophysiologically-based guidance to patient management
    • Anemia is not well-covered in most general texts, despite being the most common hematologic problem worldwide
    • The first major book in the area for over thirty-five years, despite recent advances in scientific understanding, which have led to new drugs coming to market
    • Includes access to an HTML version of the text on Cambridge Core​
    • format: Print/online bundle
    • contains: 37 b/w illus. 89 colour illus. 66 tables


Part I. The Normal Human Red Blood Cell:
1. Anemias, red cells, and the essential elements of red cell homeostasis Edward J. Benz, Jr
2. Red cell production Benjamin L. Ebert and Anupama Narla
3. Red cell lifespan, senescence and destruction Richard Kaufman
Part II. The Patient with Anemia:
4. The clinical approach to the patient with anemia Matt Quesenberry, Alina Huang and Fred J. Schiffman
5. Anemias of childhood Bertil Glader and Wendy Wong
Part III. Specific Forms of Anemia
Section 1. Microcytic Anemias:
6. Iron deficiency Paula Fraenkel
7. Sideroblastic anemias Nathan T. Connell and Edward J. Benz, Jr
8. The thalassemia syndromes David Chui and Madeleine M. Verhovsek
Section 2. Macrocytic Anemias:
9. Megaloblastic and non-megaloblastic anemias Peter W. Marks
Section 3. Hemoglobinopathies:
10. Sickle cell syndromes Maureen Okam
11. Structural Hemoglobinopathies Edward J. Benz, Jr
Section 4. Hemolytic Anemias:
12. Autoimmune hemolytic anemias Mark A. Murakami, Edward J. Benz, Jr and Nancy Berliner
13. Drug-induced hemolytic anemias Oreofe O. Odejide
14. Red cell membrane defects Patrick Gallagher
15. Malaria Michael A. McDevitt and Richard Bucala
16. Microangiopathic hemolytic anemia Elaine M. Majerus and J. Evan Sadler
17. Extrinsic non-immune hemolytic anemias Pavan K. Bendapudi and Ronald P. McCaffrey
Section 5. Hypoplastic Anemias:
18. Acquired aplastic anemia and pure red cell aphasia Daria Babushok and Monica Bessler
19. Paroxysmal nocturnal hemoglobinuria Robert A. Brodsky
20. Congenital marrow failure syndromes Anupama Narla and Benjamin L. Ebert
21. Anemia of chronic inflammation Satish P. Shanbhag and Cindy N. Roy
22. Myelodysplasia Rafael Bejar and Ida Wong
Part IV. Secondary Anemias:
23. HIV and anaemia Owen Seddon, Andrew Freedman and David T. Scadden
24. Anemia in the patient with cancer Murat Arcasoy
25. Secondary anemias associated with hematopoietic stem cell transplantation Joseph H. Antin
26. The anemia of aging Amanda J. Redig and Nancy Berliner
27. Anemia in pregnancy Ariela Marshall and Jean M. Connors
28. Anemias due to systemic diseases Ronald P. McCaffrey and Giada Bianchi
29. Transfusion therapy for anemia Joe Sweeney
30. Transfusion reactions Alex Ryder, Edward Snyder and David Unold
Part V. Management of Anemia:
31. Pharmacologic therapy of anemia Nicholas Short and Elisabeth Battinelli
32. Splenectomy: indications and consequences Sophia Fircanis, Andrew Brunner and Fred J. Schiffman
Part VI. Summary:
33. Anemias: summary, conclusions, and future prospects Edward J. Benz Jr