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Bronchoalveolar Lavage in Basic Research and Clinical Medicine 1st Edition

ISBN: 9780367705428
Διαστάσεις 25 × 17 cm



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This book providesa practical approach to bronchoalveolar lavage (BAL) and its analyses, which are used worldwide in both research and clinical settings. It includes useful guidelines with a theoretic background and provides details on microscopic and flow cytometric measurements for all known differential diagnostics made with BAL analyses, from chronic diseases like COPD and ILD via infectious diseases to inherited illness like cystic fibrosis. Includes BAL in both adult and pediatric medicine. The text is supported throughout by illustrations and clinical cases, serving as an invaluable resource for respiratory medicine and infectious disease clinicians and trainees.

Key features:

  • Uses BAL in the infectious diseases field and the search for respiratory viruses using the reverse transcription polymerase chain reaction (RT-PCR) technique, with contributions from worldwide experts.
  • Clarifies BAL technique and its diagnostic utility to respiratory physicians, cytologists, and pathologists involved in the diagnosis of pulmonary disease.
  • Provides an updated perspective on the future applications of BAL techonology to research and clinical medicine.


PART 1: PERFORMING AND ANALYZING BAL (focus on technical aspects), Bronchoalveolar Lavage: A short introduction, historical aspects, frequent cytological observations, and basic laboratory protocols, Oliver Schildgen, Tobias Stahlhut, Annegret Schlimbach, Michael Brockmann and Verena Schildgen, Technical Aspects of Performing Bronchoalveolar Lavage, Miriana d’Alessandro, Laura Bergantini and Elena Bargagli, BAL as a Research Tool, Miriana d’Alessandro and Elena Bargagli, BAL as a Diagnostic Tool, Samantha King, Emily Decurti, Terri Lebo, Jena Tisdale, Jane Baer, YongBao Wang, Mona Rizeq, Amy Frey, Bryan Borg and Edward D. Chan, PART 2: USING BAL AS A DIAGNOSTIC AND/OR RESEARCH TOOL (focus on disease related aspects), Respiratory Infections, Verena Schildgen, Vanessa Vedder, Michael Brockmann and Oliver Schildgen, Bronchoalveolar lavage findings in interstitial lung disease, LB Jehn, F Bonella, M Kreuter, J Guzman and U Costabel, BAL and Asthma, Paolo Cameli, Stefano Cattelan and Marco Guerrieri, Bronchoalveolar Lavage in Chronic Obstructive Pulmonary Disease, Parminder Singh Bhomra, Daniella Spittle and Alice M Turner, Cystic Fibrosis and Non-CF Bronchiectasis, Florian Stehling, BAL in Malignancy, Joanna Domagała-Kulawik
Lung Transplantation and donor lung repair, Nicolaus Schwerk, PEDIATRIC BRONCHOALVEOLAR LAVAGE, Richard Wong, Danielle Munce, Dehua Wang, Kelan Tantisira and Aparna Rao, PART 3: THERAPEUTIC USES OF BAL, Pulmonary Alveolar Proteinosis, Stéphane Jouneau, Pierre Chauvin, Mallorie Kerjouan, Cédric Ménard, Mathieu Lederlin, Bertrand De Latour