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Dry Eye Disease, 1st Edition

ISBN: 9780323827539
ISBN: 9780323827539
Διαστάσεις 24 × 19 cm



Ημ. Έκδοσης





1η έκδοση

Κύριος Συγγραφέας

67,00(Περιλαμβάνεται ΦΠΑ 6%)

Διαθεσιμότητα: 11-14 ημέρες


Clinically-oriented and up-to-date, Dry Eye Diseases focuses on the latest diagnostic techniques, management guidelines, and treatment options for dry eye disorders. This consolidated resource provides guidance on the clinical assessment of patients presenting with dry eye symptoms as well as a global perspectives on the use of FDA and off-label products. Practicing and trainee ophthalmologists and optometrists will find this an indispensable resource for understanding this complex disorder.
Key Features
  • Covers a range of topics, including clinical assessment, pathophysiology, the link between dry eye and system disease, and the use of FDA and off-label products as treatment options for dry eye diseases.
  • Includes a section devoted to the presence of dry eye disease in specific populations, including patients presenting with other ocular conditions, systemic pain conditions, graft-versus-host disease, Sjögren’s syndrome, and meibomian gland dysfunction.
  • Addresses the challenges associated with treating ocular pain not responsive to traditional dry eye disease treatments.
  • Features concise chapters from a team of international chapter authors, providing global perspectives on this common disorder.
  • Consolidates today’s available information on this timely topic into a single, convenient resource
Author Information
Edited by Anat Galor, MD, MSPH, Associate Professor of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, Florida


  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • List of Contributors
  • Chapter 1. Questionnaire Design and Use to Assess Dry Eye Disease
  • Design Considerations
  • How Should the Questions Be Selected?
  • How Should the Questionnaire Be Validated?
  • Statistical Analysis
  • Dry Eye Questionnaires
  • Conclusions
  • Section I. What is Dry Eye Disease (Ded)?
  • Chapter 2. Clinical Assessments of Dry Eye Disease: Tear Film and Ocular Surface Health
  • Introduction
  • Symptoms
  • Visual Disturbance
  • Tear Film Stability
  • Tear Volume and Tear Measurements
  • Damage to Ocular Surface
  • Inflammation of the Ocular Surface
  • Eyelid Evaluation
  • DED Diagnostic Test Batteries and Test Order
  • Chapter 3. Clinical Assessment of Dry Eye Disease: Nerve Health
  • Introduction
  • Anatomy of the Nerves
  • Manifestations of Compromised Nerve Health
  • Neuroimmune Crosstalk
  • Clinical Assessment of Corneal Nerve Health
  • Conclusion
  • Chapter 4. Pathophysiology of Dry Eye Disease Using Animal Models
  • Introduction
  • Clinical Findings in Animal Models of Dry Eye Disease
  • Pathophysiology of Dry Eye Disease Learned from Animal Models
  • Conclusions and Perspectives
  • Chapter 5. Pathophysiology of Dry Eye Disease Using Human Models
  • Introduction
  • Clinical Findings in Human Studies of Dry Eye Disease
  • Anterior Segment Imaging: In Vivo Confocal Microscopy (IVCM)
  • Aging and DED
  • Sex and DED
  • Environmental Factors and DED
  • Preservatives (Benzalkonium Chloride, BAK) and DED
  • Microbiome and DED
  • Summary
  • Section II. Dry Eye Disease (DED) in Specific Populations
  • Chapter 6. Sjögren’s Syndrome Dry Eye Disease
  • Introduction
  • Pathophysiology of Sjögren’s Syndrome
  • An Underdiagnosed Population in the Eye Clinic
  • Diagnostic Criteria for Sjögren’s Syndrome
  • Symptoms and Signs of DED in Sjögren’s Syndrome
  • Treatment of Sjögren’s Syndrome Dry Eye
  • Chapter 7. Graft Versus Host Disease and Dry Eye Disease
  • Introduction
  • Definition of OGVHD Diagnostic Criteria
  • Clinical Features
  • Newer Diagnostic Modalities
  • Role of Tear Biomarkers, Inflammatory Mediators, and Protein in Diagnostics
  • Treatment
  • Conclusion
  • Chapter 8. Meibomian Gland Dysfunction and Dry Eye Disease
  • Introduction
  • Anatomy and Physiology
  • Pathogenesis
  • Epidemiology
  • Diagnosis and Assessment
  • Management
  • Summary/Conclusion
  • Chapter 9. Systemic Pain Conditions and Dry Eye Disease
  • The Link Between Systemic Pain Conditions and Dry Eye
  • Systemic Pain Conditions Associated with Dry Eye
  • Medications in Systemic Pain Conditions That may Aggravate Dry Eye
  • Conclusions and Clinical Implications
  • Chapter 10. Glaucoma and Dry Eye Syndrome: Double Trouble
  • Introduction
  • Dry Eye in the Glaucoma Patient
  • How to Treat Glaucoma in the Dry Eye Patient
  • Conclusion
  • Section III. Treatment of Dry Eye Disease (DEF)
  • Chapter 11. Treatment of Dry Eye Disease in the United States
  • Introduction
  • Nonpharmacologic Treatments
  • Prescription Drugs
  • Blood Products
  • Eyelid Procedures
  • Devices
  • Surgical Procedures
  • Pipeline
  • Conclusion
  • Chapter 12. Treatment of Dry Eye Disease in Asia
  • Introduction
  • Current Dry Eye Therapies in China
  • Dry Eye Therapy in Japan Based on TFOD and TFOT
  • Treatment of Dry Eye in Korea
  • Dry Eye Therapy in Singapore
  • Epidemiology, Diagnosis, and Treatment of Dry Eye Disease in Taiwan
  • Dry Eye Therapy in Thailand
  • Overview of Dry Eye in Vietnam
  • Conclusions
  • Chapter 13. Treatment of Dry Eye Disease in Europe
  • European Dry Eye Society
  • Definition of DED in Europe
  • Classification of DED in Europe
  • Epidemiology of DED in Europe
  • Dry Eye Diagnosis in Europe
  • Subjective Symptoms of DED
  • Clinical Signs of DED in Europe
  • Treatment of DED in Europe
  • Artificial Tears
  • Artificial Tears with Specific Additives
  • Artificial Tears with Lipids
  • Lid Hygiene
  • Intense Pulsed Light Treatment
  • Preservation of Tear Film
  • Antiinflammatory Treatment in DED in Europe
  • Antibiotic Treatment in DED
  • Autologous Serum
  • Chapter 14. Treatment of Meibomian Gland Disease
  • Chapter 15. Treatment of Ocular Pain Not Responsive to Traditional Dry Eye Disease Treatments
  • Introduction
  • Topical Therapies for Peripheral Sensitization
  • Systemic Therapies for Central and Peripheral Sensitization
  • Procedural Therapies
  • Complementary Therapies
  • Conclusion
  • Chapter 16. Pathways and Mechanisms of Ocular Pain and Photophobia in Dry Eye Disease
  • Introduction
  • Dry Eye Disease
  • Corneal Nerves and Pain Receptors
  • Ascending Pathways of Pain
  • Neuropathic Pain and Photophobia
  • Distinguishing Nociceptive and Neuropathic Pain
  • Conclusion
  • Index