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Environmental Stressors and OxInflammatory Tissues Responses

ISBN: 9781032357003
ISBN: 9781032357003
Διαστάσεις 25 × 18 cm



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180,00€(Περιλαμβάνεται ΦΠΑ 6%)

Διαθεσιμότητα: 23-28 ημέρες


Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation –  impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major findings. This book is a state-of-the-art summary of these myriad severe life stressors. The chapters on the different pollutants focus on disease mechanisms (cardiovascular, neurological and metabolic disorders) and on oxidative stress and inflammation. The editors emphasize emerging mechanisms based on dysregulation of the circadian clock, the microbiome, epigenetic pathways, and cognitive function by environmental stressors, and introduce the exposome concept while highlighting existing research gaps.

Key Features:

  • Links various environmental stressors to the incidence of noncommunicable diseases
  • Includes chapters on airborne toxins, chemical pollutants, noise, and ultraviolet radiation stressors
  • Contributions from an international team of leading researchers
  • Summarizes the impacts of stressors on disease mechanisms


Section 1 – Conceptual

Chapter 1

Man-made environment or living in the Anthropocene – a major health risk factor in the 21st century

Andreas Daiber and Giuseppe Valacchi

Chapter 2

The exposome concept – description of life-long environmental exposure effects on metabolism, health and disease

Andreas Daiber, Giuseppe Valacchi, Matthias Oelze, Marin Kuntic, Thomas Münzel

Chapter 3

Problems related to the use of biomarkers of oxidative stress in disease

Pietro Ghezzi & Henry Jay Forman


Section 2 – Airborne toxins


Chapter 4

Formation, interconversion, and buffering of reactive oxygen species from gaseous and particulate air pollutants in epithelial lining fluid

Thomas Berkemeier & Ulrich Pöschl

Chapter 5

Chemical modification of proteins by reactive oxygen and nitrogen species under atmospheric and physiological conditions

Janine Fröhlich-Nowoisky, Kurt Lucas, Thomas Berkemeier, Ulrich Pöschl

Chapter 6

Air pollution and neuropsychiatric disease

Omar Hahad, Thomas Münzel, Donya A. Gilan, Maria Teresa Bayo Jimenez, Jasmin Ghaemi Kerahrodi

Chapter 7

Underlying mechanisms of the effects of particulate matter in primary and distant organs

Natalia Magnani, Timoteo Marchini, Agustina Freire, Sofía Reynoso, Silvia Alvarez, Pablo Evelson

Chapter 8

The ocular surface as a target of air pollution

Romina M. Lasagni Vitar, Ailen Gala Hvozda Arana, Timoteo Marchini, Pablo A. Evelson, Sandra M. Ferreira

Section 3 – Other chemical pollutants

Chapter 9

Environmental heavy metals, oxidative stress and disease potential – NRF2 centered genetic and epigenetic mechanisms

Xinpei Lin, Fuli Zheng, Filipe Marques Gonçalves, Yumi Abiko, Huangyuan Li, Yoshito Kumagai, Michael Aschner

Chapter 10

Insights into the non-coding-RNA regulation of environmental stress-induced disease

Veronica Miguel & Cristina Espinosa-Diez

Chapter 11

Oxidative and inflammatory potential of nano/microplastics in living organisms

Konrad Wojnarowski, Moyan Hu, Dusan Palić

Chapter 12
Micro- and nanoplastics contamination: an emerging environmental issue for skin health
Alessandra Pecorelli & Giuseppe Valacchi

Chapter 13

Waterpipe smoking and e-cigarettes: a safer alternative to combustible cigarettes?

Andre Faria, Arthur Faria, Ismail Laher

Chapter 14

The aryl hydrocarbon receptor as an environmental sensor and mediator of stress and inflammation

Christoph F. Vogel & T. Haarmann-Stemmann


Section 4 – Other physical stressors (Noise & UV & EMF)

Chapter 15

Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases

Katie Frenis, Omar Hahad, Thomas Münzel, Andreas Daiber

Chapter 16

Noise pollution and neuropsychiatric disease

Omar Hahad, Thomas Münzel, Donya A. Gilan, Maria Teresa Bayo Jimenez, Jasmin Ghaemi Kerahrodi

Chapter 17

Imaging of metabolic activity adaptations to UV stress and differentiation at cellular resolution in skin and skin equivalents – Implications for oxidative UV damage

Florian Gruber & Christopher Kremslehner

Chapter 18

Adverse health effects of UV on skin and other organs

Giuseppe Valacchi & Francesca Ferrara

Chapter 19

Mechanistic insights into EMFs induced neuronal oxidative damage

Giorgia Innamorati, Barbara Benassi, Claudia Consales


Section 5 – Mental stress

Chapter 20

How adverse childhood experiences increase inflammation and oxidative stress

Jasmin Ghaemi Kerahrodi & Matthias Michal

Chapter 21

The role of oxidative stress in cardiovascular disease caused by social isolation and loneliness

Huige Li & Ning Xia