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General and Comparative Endocrinology An Integrative Approach 1st Edition

ISBN: 9781032416847
ISBN: 9781032416847
Διαστάσεις 28 × 21 cm



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General and Comparative Endocrinology: An Integrative Approach, takes a holistic approach to endocrinology, introducing students to the diverse facets of this interdisciplinary science ranging from the medical to comparative domains, while also exploring evolutionary, environmental, and conservation specializations within the field. The textbook is founded on the principle that students interested in the health sciences will benefit from understanding how proficiency in endocrine function among a diversity of organisms contributes to advances in modern medicine. Likewise, students intrigued by comparative physiology will benefit from the wealth of knowledge derived from medical/clinical endocrinology, the historical bedrock of the field. This textbook represents the modern field of endocrinology in its totality by addressing topics and recent advances not currently discussed in other introductory endocrinology textbooks.

Key Features

  • Introduces the broad and interdisciplinary scope of endocrinology.
  • Provides clear chapter objectives and key concepts.
  • Includes summary and synthesis questions for each chapter that are suitable for exams and quizzes.
  • Includes a chapter devoted to endocrine-disrupting chemicals.
  • Describes the roles played by the endocrine system in important health challenges related to appetite regulation, obesity, diabetes, and other diseases stemming from ‘mismatches to modernity’.
  • Integrates evolutionary and comparative approaches to hormones and health.




Author Biography

List of Abbreviations

Unit Overview Unit I. Introduction to Endocrinology

1. The Scope and Growth of Endocrinology

2. Fundamental Features of Endocrine Signaling

3. Evolution of Endocrine Signaling

Unit Overview Unit II. Mechanisms of Hormone Action

4. Hormone Classes and Biosynthesis

5. Receptors

6. Receptor Binding Kinetics

Unit Overview Unit III. Neuroendocrinology

7. Neurosecretion and Hypothalamic Control of the Pituitary

8. The Pituitary Gland and Its Hormones

9. Central Control of Biological Rhythms

Unit Overview Unit IV. Developmental Endocrinology

Thyroid Hormones. Development and

11. Insect Molting and Metamorphosis

12. Calcium/Phosphate Homeostasis, Skeletal Remodeling, and Growth

Unit Overview Unit V. Stress, Blood Pressure, and Ion Balance

13. The Multifaceted Adrenal Gland

14. Adrenal Hormones and the Stress Response

15. Blood Pressure and Osmoregulation

Unit Overview Unit VI. Appetite, Digestion, and Metabolism

16. Digestion

17. Appetite

18. Energy Homeostasis

19. Metabolic Dysregulation and Disruption

Unit Overview Unit VII. Reproduction

20. Sexual Determination and Differentiation

21. Male Reproductive System

22. Female Reproductive System

23. The Timing of Puberty and Seasonal Reproduction

24. Pregnancy, Birth, and Lactation

Unit Overview Unit VIII. Endocrine-Disrupting Chemicals

25. EDCs: Assessing the Risk

Appendix 1. Endocrine-Related Nobel Prizes Awarded in the Last Century

Appendix 2. Some Examples of Endocrine Breakthroughs Using Non- Mammalian Model Organisms

Appendix 3. Classical and Modern Concepts in Endocrinology

Appendix 4. Some Vertebrate and Arthropod Hormones and Their Characteristics

Appendix 5. Some Diseases Associated with GPCR Dysfunction

Appendix 6. Some Diseases Associated with Nuclear Receptor Dysfunction and Their Treatments

Appendix 7. The 48. Known Members of the Human Nuclear Receptor Family Categorized According to Sequence Homology

Appendix 8. Primary Enzymes of Steroid Hormone Biosynthesis

Appendix 9. A Summary of Steps in Human Digestion

Appendix 10. Failures in Contraceptive Function during the First Year of Use

Appendix 11. Secondary Sexual Characteristics in Females and Males Associated with Puberty

Appendix 12A. Tanner Stages of Breast and Pubic Hair Development in Females

Appendix 12B. Tanner Stages of External Genitalia and Pubic Hair Development in Males

Appendix 13. Classifications of Some Common Endocrine-Disrupting Chemicals