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Cancer Vaccines: From Research to Clinical Practice

77,00

Εκδόσεις:
ISBN: 9781138112605

Επιπλέον πληροφορίες

Εκδόσεις

Ημ. Έκδοσης

2017/09

Σελίδες

280

Μορφή

Έντυπο

23-28 ημέρες

Περιγραφή

Features

  • Critically analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential
  • Discusses “theranostics” as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy
  • Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer
  • Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them

Summary

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: From Research to Clinical Practice is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist.

Cancer Vaccines: From Research to Clinical Practice:

  • Analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential
  • Discusses “theranostics” as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy
  • Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer
  • Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them

Περιεχόμενα

SECTION I – Basic Aspects: Tumor Antigens and Preclinical Modelling

1. Factoring in antigen processing in designing anti-tumor T-cell
vaccines, Lévy, Colombetti, Janda, Chapatte, Alves, Casado, Lévy and
Peitrequin

2. Outlining the gap between preclinical models and clinical situation, Daniel L. Levey

SECTION II – Cell Based, Anti-infectious and Personalized Vaccines

3. THERAPEUTIC AND PROPHYLACTIC CANCER VACCINES – EMERGING
PERSPECTIVES FROM ALLOGENEIC AND INFECTIOUS DISEASE VACCINES, Srinivasan

4. Personalized Cancer Vaccines, Teofilovici, Wentworth

5. Dendritic cell vaccines for gliomas, Luptrawan, Liu, S. Yu and Brian

III. INTRACEREBRAL HEMORRHAGE (ICH)

6. Peptide based active immunotherapy in cancer, Schroter and Minev

7. Multimodality Immunization Approaches to Improve on DNA Vaccines for Cancer, Qiu and Smith

8. Bidirectional Bedside Lab Bench Processes and Flexible Trial
Design as a Means to Expedite the Development of Novel
Immunotherapeutics, Bot and Obrocea

9. Diagnostic approaches for selecting patient-customized therapies,
obviating tumor variability to maximize therapeutic effect, Chang,
Kertesz, Liu

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