• -8%-8% KCNQ2- and KCNQ3-Associated Epilepsy

    KCNQ2- and KCNQ3-Associated Epilepsy

    Alfred L. George, Jr

    Part of Elements in Genetics in Epilepsy

    KCNQ2 and KCNQ3 encode subunits (KV7.2, KV7.3) that combine to form a voltage-gated potassium ion (K+) channel responsible for generating an ionic current (M-current) important for controlling activity in the nervous system. Pathogenic variants in both genes are associated with a spectrum of genetic neurological disorders that feature epilepsy of variable severity and can be […]

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